Basic Info.
Type
Synthesis Material Intermediates
Delivery Time
Within 2-3 Working Days
Keywords
Nicotinamide Adenine Dinucleotide
Keywords 1
Nicotinamide Adenine Dinucleotide Price
Keywords 4
Sell Nicotinamide Adenine Dinucleotide
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Nicotinamide Adenine Dinucleotide Powder
Transport Package
20kg Per Carton
Specification
20kg per carton
Product Description
99 % beta-nicotinamide adenine dinucleotide disodium salt NADH cas 606-68-8
Introduction
Products name | NADH(b-Nicotinamide-Adenine Dinucleotide) |
Specification | 99% |
CAS No. | 606-68-8 |
Appearance | White powder |
Certificates | ISO, Halal , Kosher, CQC, IQNET |
M.F | C18H36N2O12 |
EINECS No | 210-123-3 |
Information
Product name:Nicotinamide Adenine Dinucleotide
CAS No.:606-68-8
M.F.:C21H27N7Na2O14P2
Purity: 99% min
Appearance:White Powder
Nicotinamide Adenine Dinucleotide is a water-soluble vitamin, The product is white crystalline powder, odorless or nearly odorless, bitter in taste, freely soluble in water or ethanol, dissolvable in glycerin.
Nicotinamide Adenine Dinucleotide is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.
In addition, Nicotinamide Adenine Dinucleotide has prevention and treatment of heart block, sinus node function and anti-fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.
Functions
Nicotinamide adenine dinucleotide, abbreviated NADh+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide.
In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another. The coenzyme is, therefore, found in two forms in cells: NAD+ is an oxidizing agent - it accepts electrons from other molecules and becomes reduced. This reaction forms NADH, (Nicotinamide adenine dinucleotide) which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD+. However, it is also used in other cellular processes, the most notable one being a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. Because of the importance of these functions, the enzymes involved in NAD+ metabolism are targets for drug discovery.
In organisms, NAD+ can be synthesized from simple building-blocks (de novo) from the amino acids tryptophan or aspartic acid. In an alternative fashion, more complex components of the coenzymes are taken up from food as the vitamin called niacin. Similar compounds are released by reactions that break down the structure of NAD+. These preformed components then pass through a salvage pathway that recycles them back into the active form. Some NAD+ is also converted into nicotinamide adenine dinucleotide phosphate (NADP+); the chemistry of this related coenzyme is similar to that of NAD+, but it has different roles in metabolism.
Nicotinamide adenine dinucleotide, abbreviated NADh+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide.
In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another. The coenzyme is, therefore, found in two forms in cells: NAD+ is an oxidizing agent - it accepts electrons from other molecules and becomes reduced. This reaction forms NADH, (Nicotinamide adenine dinucleotide) which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD+. However, it is also used in other cellular processes, the most notable one being a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. Because of the importance of these functions, the enzymes involved in NAD+ metabolism are targets for drug discovery.
SpecificationTest items | Specification |
Appearance | White to yellowish lyophilized powder |
Purity determined by | |
Enzymatic Assay (ADH) | ≥ 95% |
HPLC | ≥ 95% |
NADH contents (anhydrous basis) | ---- |
Water contents | < 8% |
Na contents | 6.5±1.5% |
β-NAD (HPLC) | <2% |
Organic residues (as ethanol) determined by GC: | < 0.1% |
Heavy metals (as Pb) | ≤ 5ppm |
Arsenite (As) | ≤ 1ppm |
NADH (A340, ε= 6.3 (1×mmol-1×cm-1) | ≥ 90% |
NADH (A260, ε= 14.3 (1×mmol-1×cm-1) | ≥ 90% |
Ratio at pH 10 | |
A250/A260 | 0.82±0.03 |
A280/A260 | 0.23±0.02 |
A340A260 | 0.43±0.01 |
pH value in water(100mg/ml) | 7.0-10.0 |
Total Bioburden | <100 CFU/g |
Coliform | <100 CFU/g |
Yeast and moulds | <100 CFU/g |
Salmonella | negative |
Staph.aureus | negative |
E.coli | negative |
why choose our comp
any
1. quality
our products meet msds safe standard and we have iso and other certificate so yan can get high quality products from our company.
2. price
we are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
3.packing
we can do according to the customers' request.
4.transport
ems,dhl, tnt, ups ,fedex, by air, by sea
dhl express, fedex and ems for quantity less than 50kg, usually called as ddu service;
sea shipping for quantity over 500kg; and air shipping is available for 50kg above;
for high value products, please select air shipping and dhl express for safe;
5.service
we offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
we will try our best to satisfied you.
1. tailor-made for every customers.
2. third-party test for the products you demand.
3. test your counter-samples and produce them for you.
4. best discount for old customers.
Thanks for your considering of Hebei Guanlang Biotechnology Co., Ltd.(Crovell). Crovell is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.
Crovell is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,
such as phenylacetamide etc., Crovell also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.
After ten years development,Crovell has become a Diversified development company,not only involves in chemicals, but also real estate ,clothes ,agricultural products and so on.
So far, Crovell has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,Crovell can always make the product quality best, some of the products from Crovell can reach the purity of 99.9+, such as 2-phenylacetamide. This is the important reason for customers who choosing Crovell.
In future, Crovell must become to a more important trade bridge for china and foreign countries especially in pharmaceutical industries.
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 10 days when get the payment.
Shipping :
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR
Q: How to start orders or make payments?
A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q: What's your MOQ?
A:For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantity, we always support with better price.
Q:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q:How to contact us ?
You can choose your interested products and send inquiry to us.You can dial our telephone directly, you will get our reply.
Send Email to us.
Address:
Qiaoxi District, Shijiazhuang, Hebei, China
Business Type:
Manufacturer/Factory
Business Range:
Chemicals, Health & Medicine, Service
Management System Certification:
ISO 9001, ISO 9000, ISO 14001, ISO 14000, ISO 20000, IATF16949, GMP
Company Introduction:
Hebei Guanlang Biotechnology Co., Ltd. is the leading manufacturer for cosmetic materials in China.
Which located in Shijiazhuang, Hebei Province.
We are specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,
After ten years development, Hebei Guanglang Biotechnology Co, . Ltd has become a Diversified development company, not only involves in chemicals, but also real estate, clothes, agricultural products and so on.
So far, Hebei Guanglang Biotechnology Co, . Ltd has business in more than 35 countries, most big customers come from Europe and America, because among the suppliers in China, Crovell can always make the product quality best, some of the products from Crovell can reach the purity of 99.9+, such as carbomer. This is the important reason for customers who choosing Crovell.
In future, Hebei Guanglang Biotechnology Co, . Ltd must become to a more important trade bridge for China and foreign countries especially in pharmaceutical industries